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they sort of are open. your brain is basically a interpreting and predicting the world 24/7. it work by making meaning of what it perceives. a flood of a neurotransmitter basically alters the way the brain works and whatever experience you have is your brain trying to make senses of the new and unexpected electrochemical activity.

you are not communicating with your dead mother or you are not being a god.

it works for depression because it allows the brain to exercise and form neural pathways that are not normally allowed. even if we think about the brain as one organ, in reality there are a lot of interconnected neural nets that are regulated by a central supervisory net called the DMN. Under psychedelics, the DMN shuts down while the other networks increase activity.




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