Respectfully, are you a doctor? I am not. That link is from 2007 and talks about a modified Adenovirus. There’s so much medical jargon in there that I can’t make any sense of it, let alone connect it to increased risk of strokes for an Adenovirus based COVID vaccine. I understand why vaccines can be scary but ask yourself this: is your unease based on a deep medical understanding of the subject matter, or an underbelly feeling?
I believe you may be confusing adenovirus vaccines and vaccines that use adenovisues as vectors. The former protects against adenovirus infection, the later uses an adenovirus as a vector to vaccinate against some other virus.
There is a sort of common adenovirus vaccine [1].
Adenovirus as a vector is new. There is an adenovirus vector Ebola virus that is approved. I think that is the only one. The only others deployed are for COVID under emergency use authorizations. There are several for other diseases in development, but the farthest along are still in clinical trials.
What the comment basically said is that adenovirus on it's own produced coagulation aka clotting, but that PEG wrapping decreases coagulation a lot. Therefore, a vaccine embedded in PEG, like those made by BioNTech and Moderna, should lead to less coagulation.
