If Clojure offered a direct compile-to-native option for any platform (desktop/mobile/WASM) with no JVM in between, I suspect it would explode in popularity.
I don't know of a specific example, but Lisps have a pretty long tradition of coming with architecture specific assemblers. I'm sure there are many CL implementations that can target ARM.
The problem is any sizable Lisp needs quite a lot of stuff available at runtime. A trivial program would still likely[0] be a sizable blob with a memory penalty.
If anything, I'd say Clojure (cljs especially) actually bypasses this problem by leveraging a platform's privileged language. Purely theoretically, there's no reason why you couldn't have a mobile device built around CL. But if you want to target what's already out there, a parasitic design works much better.
Also, on the popularity front I guess it's a bit of a glass half full situation. Compared to other Lisps, Clojure is no doubt dominating. Among what I'd call "alternative languages" it's a tough call.
[0] Have to mention there's a lot of diversity in CL implementations so this is certainly not universally true. But I would assume this is true for something that has all the conveniences you'd want.
Wasm was designed for C/C++ and pretty hostile toward dynamic GC languages. Clojure is very different from C++ and can leverage JSVM GC and dynamic dispatch system, which are a lot of code and highly optimized.
Even disregarding the perf problems the scale of implementation effort and resulting wasm code size would be prohibitive. Not to mention losing easy low friction interop with JS ecosystem libraries.
For that track of thought - There are some more static nascent Clojure inspired languages around that might fit. Eg this one, doesn't have GC either: https://github.com/carp-lang/Carp
