"fatigued" from not getting enough sleep or being physically active is not the same thing as folks get from diseases. When you are fatigued from children, you can sleep and take care of it. It is solvable.
It isn't like that with disease.
The worse I've had is the complete inability to stand long enough to make a simple dinner, for example, and this was after napping and sitting most of the day. I'm lucky: Mine passed. Some people live with this day after day after day, and this is more similar to what folks with disease-related fatigue.