The human eyeball has diameter roughly equal to the entire length of this lizard, making its volume 10,000X larger than the lizard's eyeball.
OTOH, with a pupil that small, visual depth of field must be large. So perhaps the nano-chameleon doesn't need to do much in the way of focussing.
Small wonder they took so long to discover :-p
But the pupil is also small enough that diffraction is a major issue so their visual acuity is probably quite poor