As pointed out in some other comments, SpaceX do extensive simulations, they almost certainly have the best rocket simulations in the world (see some of the published talks on youtube to see the state of their research).
We know that their simulations/calculations were excellent for these last couple of Starship tests because the tests themselves were excellent. There were a number of things being tested, including things like flying multiple Raptor engines, turning those engines off, switching between different fuel tanks for launching and landing, the bellyflop maneauver, the landing flip maneauver, engine relight from the header tank, and finally landing. Almost all of these were perfect, from what information we have.
There have been two failures, and from what we know these were not related to simulations at all - they seem to be system/integration issues, though we don't really know much about the engine failing to relight this test.
On SN8 they had a pressure issue feeding the engines from the header tanks. It may have been possible to anticipate this or test it independently, but it was probably the least important of all the things being tested. Given that they have multiple new (and updated!) test articles rolling off the production line they clearly made the choice to conduct the test without spending years trying to validate every single component. Again, they obviously did a lot of excellent engineering despite not undertaking a long pre-flight validation, as the test was so succesful.
We know that their simulations/calculations were excellent for these last couple of Starship tests because the tests themselves were excellent. There were a number of things being tested, including things like flying multiple Raptor engines, turning those engines off, switching between different fuel tanks for launching and landing, the bellyflop maneauver, the landing flip maneauver, engine relight from the header tank, and finally landing. Almost all of these were perfect, from what information we have.
There have been two failures, and from what we know these were not related to simulations at all - they seem to be system/integration issues, though we don't really know much about the engine failing to relight this test.
On SN8 they had a pressure issue feeding the engines from the header tanks. It may have been possible to anticipate this or test it independently, but it was probably the least important of all the things being tested. Given that they have multiple new (and updated!) test articles rolling off the production line they clearly made the choice to conduct the test without spending years trying to validate every single component. Again, they obviously did a lot of excellent engineering despite not undertaking a long pre-flight validation, as the test was so succesful.