There has been a slow-simmering pop-hypothesis, fueled by a number of accidents such as AF 447, that Airbus' approach to fly-by-wire controls is less intuitive than Boeing's in a crisis. As far as I know, there is no real evidence for this making Airbus planes less safe, but until the 737 Max crashes, I think there was, if anything, a bias against Airbus.
I couldn't find any data on the number of journeys per year. The statistic is useless as an indicator of safety as it isn't normalized to either a unit of distance or journey.