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Yes. Treatment resistant depression for about... 5 years or so, with it getting so bad recently (in this year) that I've just about given up on life.



Assuming you've tried the medication route, there's one that not too many psychiatrists are aware of for its off-label depression use, specifically for treatment-resistant depression: Modafinil.

Don't let a cursory search warn you off, it is not a traditional stimulant, and not considered addictive. It can also be an excellent second-line treatment for depression. It's what keeps me functional during periods where depression bleeds through my normal treatment plan. Check out this article: https://pubmed.ncbi.nlm.nih.gov/16035049/




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