This seems like the sort of argument that should be distributed in the peer-revi...

This seems like the sort of argument that should be distributed in the peer-reviewed literature to scientists, not on a news website.

I am far from average in my consumption of medical literature--I read several papers every week and have some (limited) background in biophysics. Nonetheless, this debate is miles over my head. One would need to know a great deal about pharmacology to evaluate this article. There are lots of reasons to use one prodrug over another; likewise, there are a great deal of differences between animal models and humans.