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This is the same thing as a vaccine (but without doing the safety due diligence). IMHO as a not-medical-professional, we’d be better off with just using one of the (dead) vaccine candidates early than with a slightly attenuated live virus.

We actually started clinical trials of the Moderna mRNA vaccine in humans a month ago. We may have some early safety data. Better that than intentionally exposing people.




No it is not. There is still safety data, it has just been done by nature and not by jabbing people in the arm with some experimental vaccine.


No, the safety data is not well controlled in this case. There are lots of ways to administer a vaccine, it doesn't have to be injection.

Look up the history of vaccination. Starting in the late 18th Century, people used to do this exact thing for early vaccinations: they found a naturally occurring, less pathogenic strain (for instance, cowpox[1] in the days of smallpox), and intentionally exposed people. This is exactly the same thing as a vaccine except less controlled and, ultimately, much less safe.

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[1]The root of "vaccine" is "vacca," i.e. Latin for "cow," for this reason.


Safety data can be gained from epidemiology studies. There is more than one way to work out if a treatment is safe and effective.


Epidemiological studies are much poorer than clinical trials. I’d rather have low-N but well controlled clinical trials than nebulous epidemiological studies.


Of course, but in this pandemic we shouldn’t let the perfect be the enemy of the good. Waiting for the perfect vaccine to be developed will have a very high cost. There are no easy options here.




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