Unless you have the military enforce the lockdown, people will eventually refuse to starve quietly in their houses and will brave the "terrifying" 1% chance of death from COVID to go back to being alive.
Honestly, with the governor this morning toying with "about 18 months", we are agreeing to give up more than 1% of our life just to reduce the risk of the 1% chance of death.
If you do order the military to enforce it, you are likely to end up with a civil war. Some people will eventually resist, and then either the army starts firing on Americans or they let people go on with their lives.
On a more personal note, the mental health cost of perfect social isolation is already getting to me, and frankly, I don't think I would survive more than a bare couple of months, even if the magic goods fairy delivered me every essential item I could ever want in infinite quantity.