Business systems: inventory, sales orders, purchasing, forecasting, accounting, etc.
One is one of the largest master distributors of industrial supplies in the world.
Another is a web-based and catalog distributor of consumer goods (mostly apparel.)
Each has acquired 5 competitors in the past 10 years, converting all of them from whatever they were running to their 20+ year old software written in 40+ year old technology. Both were super agile long before any of us ever used the term.
(All client side web software is written in javascript. Some things do change.)
I assume that since it's mostly industrial, they don't have a thousand hits a day, etc., form random web gawkers looking to buy a doodle for their home?
I don't think his point is about what's subjectively the best language to build websites, but rather that language is not the focus of how to make a highly successful business.