I thought that too. Building muscles to protect and support ligaments to me sounds like a decent solution. I feel like people who are underweight are the ones that are most prone to suffer from RSI.
Well, be careful. I love trackballs, and have used them exclusively for 25+ years. But... “trackball thumb” is a thing. I had a physical therapist show me how to work out issues when I get them, but ultimately the healthiest thing for me to do is to switch between 3 different trackballs to change up the motions.
I use one of those at work, and a mouse at home. I like to think mixing up the motions helps, but honestly it's because I'm not nearly precise enough to game with a ball.
I've been using a SlimBlade for about 10 years now and really like it. Spinning the ball for the mousewheel was brilliant and the giant, centered ball gives you a lot of freedom in how to position your hand on it. They are also have nice quality builds, I've only just had to buy a replace recently after many years.