Binary wheels aren't out from everyone you mentioned yet (they are for NumPy and SciPy... but the maintainers of most of the packages you mention appear to usually wait for their next releases before getting the wheels out), but a NumPy + SciPy + Matplotlib + Pandas + Scikit-learn setup was functional before 3.8.0 was released (I had one spinning during the betas, one just has to be willing to compile things from source usually).