This isn't a problem with the syntax, you could just have macros consume and produce lists and avoid this entirely. In fact, there already exist reader macros that implement pretty much exactly this syntax but for Lisp: https://docs.racket-lang.org/sweet/index.html
Right, so you need to support mixing some lists in, to complement meaningful whitespace, the way sweet-expressions or SRFI-49 do. But that's exactly because the consequences of "whitespace only" syntax are too severe.
