I'm not a great resource of Silicon Valley startup advice, but if you need any help with the technical aspects (such as rewrite rules so you don't have URLs that look like /~svstartu/index.php?title=Main_Page ;), or if you need a skin, MediaWiki extension, etc, I'd be happy to help. I have some experience with the internals of MediaWiki.
EDIT: Also, for others looking where to start, take a peek at this page for a full list of pages that need to be created: http://svstartup.com/~svstartu/index.php?title=Special:Wante...