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Emphasis on possibly: Olney's lesions have never once been observed in a human being



yes, definitely - it probably has something more similar to the safety profile of amphetamines in terms of physical safety, which isn't perfect, but seems to not worry RXing adderall to large swaths of people.

Though it also seems there is something going on neurotransmitter wise that seems to have a more marked effect on immediate anhedonia/depression/fatigue in the aftermath and anecdotally for some people that starts looking a little cumulative.

(ie; someone that uses a lot of MDMA for a few years finds that the depressive hangovers get worse and worse and eventually get to the point where it takes a few months of non-use to even get totally 'right' again)




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