Vyvanse is a legally controlled substance in the US, so there is plenty of information publicly available on the subject. The most common side effects off the top of my head are reduced appetite, increased blood pressure, and sleep problems.
I've been taking Vivance for years. FWIW, I had some of those side effects when I first started taking it and they have subsided for me. I still feel like I benefit from the medication and haven't ever felt like 'abusing' it.