More info on niacin/tryptophan https://www.youtube.com/watch?v=yofewUE6L-k https...

mrpinc · on March 25, 2019

I took niacin once in pill form and it made my body burst out into a fierce itch rash that lasted about an hour.

dekken_ · on March 25, 2019

That's know as a "niacin flush" AFAIK - you might have taken too much too soon

rubicon33 · on March 25, 2019

From the article, they mentioned that taking tryptophan or eating foods with tryptophan in them, reduces the uptake of tryptophan due to amino acid competition:

> There is competition between the various amino acids for the transport system, so after the ingestion of a meal containing protein, the rise in the plasma level of the other large neutral amino acids will prevent the rise in plasma tryptophan from increasing brain tryptophan

So possible OP took it on an empty stomach which spiked the levels in the body?

swozey · on March 25, 2019

This is extremely common with niacin ingestion. If you look up a lot of pre-workout drinks (no xplode for a specific example) it's one of the most common complaints/mentions.

I haven't used it in forever but when I did sort of just got accustomed to being itchy until it wore off. I've read that it can cause liver issues, though. I just quit taking pwo's altogether.