I suppose so. I don't know much about eGPUs. I see the cheapest one available on the Apple store is $700 which includes a Radeon Pro 580 (appears to be the same card offered on the top of line iMac from today?). With SSDs on the Mini being as expensive as they are ($800 to upgrade to 1TB), I'd probably want an external HD as well, so minimum 3 boxes on my desk and more chords to deal with.
It would meet my needs and I might reluctantly get one.
It would meet my needs and I might reluctantly get one.