Agree with other reply that tptacek has a good take. One thing to keep in mind is that glutamates play a role as neurotransmitters. It’s possible that if large doses are taken on an empty stomach they may exacerbate some insomnia symptoms.
It’s unclear how much of an effect it has though. Just like tryptophan in large doses can cause drowsiness. However for instance people eating turkey and getting sleepy assume it’s the tryptophan when really it’s just the large quantities of food they just ate, and the tryptophan really has no effect.
So like tptacek says... could be the sodium. But also dont just dismiss the role of glutamate out of hand.
And even if it does cause issues in some people, it’s probably also totally safe based on all the evidence.
It’s unclear how much of an effect it has though. Just like tryptophan in large doses can cause drowsiness. However for instance people eating turkey and getting sleepy assume it’s the tryptophan when really it’s just the large quantities of food they just ate, and the tryptophan really has no effect.
So like tptacek says... could be the sodium. But also dont just dismiss the role of glutamate out of hand.
And even if it does cause issues in some people, it’s probably also totally safe based on all the evidence.