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That could be true even if the MSG happens to give you an awful headache in the short term.




[0] is shill work by researchers working for a MSG manufacturer. I have seen this before. One even has an "ajiusa.com" e-mail address right there, /palmface/. Can't comment on on [1]: the entire paper is paywalled as far as I can see, not even a hint at the results.

Let's try something else:

Graham TE, Sgro V, Friars D, Gibala MJ. 2000. Glutamate ingestion: the plasma and muscle free amino acid pools of resting humans. American Journal of Physiology-Endocrinology and Metabolism 278:E83–89.

These researchers provided single 150mg/kg oral doses of MSG to 9 healthy volunteers (8 males, 1 female) to determine the plasma and muscle concentrations of glutamate following ingestion. All volunteers reported transient headaches.

Shimada A, Cairns BE, Vad N, Ulriksen K, Pedersen AML, Svensson P, Baad-Hansen L. 2013. Headache and mechanical sensitization of human pericranial muscles after repeated intake of monosodium glutamate (MSG). Journal of Headache and Pain 14:2

More than 50% of healthy, male subjects given 150mg/kg daily doses developed headaches.


> Let's try something else

N=8 or 9 (low power), 150 mg/kg(!) doses.

That's like ingesting 11 g of the stuff for a 75 kg adult.


from [0]:

>Because of the absence of proper blinding, and the inconsistency of the findings, we conclude that further studies are required to evaluate whether or not a causal relationship exists between MSG ingestion and headache.


And that's from people paid by their boss to show that there is no such effect.




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