Gaming is one of the use cases where native wins, specially since WebGL 2.0 isn't widespread and it only exposes a subset of OpenGL ES 3.0, let alone GL ES 3.1, 3.2, Metal or Vulkan.
However if the game is a Flash like one, then WebGL/WebAssembly might just be enough.
However if the game is a Flash like one, then WebGL/WebAssembly might just be enough.