For real though, the difference between 60 and 144 is night and day. I can't go back to 60 after playing with 144. I wonder if going beyond 144 would have the same effect.
A frame is 1/60 of a second (generally), so if you are indexing your frames with a 32-bit integer, you have enough for 2.26 years of video (or video game, or whatever).
What do you mean by a 'frame' and how does 2.26 years relate to a frame?