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"Oh here's a new biochemical path connected to exercise."

"Oh sweet I guess I should exercise then."

Except the basis for the decision to exercise or not has already been confirmed in inumerous ways on these grounds, and it is redundant since we should expect massive stress of any sort (exercise included) to result in large cascading changes in the body.

Or the other way around, the body is so intricate that any individual biochemical pathway is unlikely to play a significant role in the whole, and so we should explain things in terms of the whole to actually learn something. The OP mentioned mood. But there are a lot of unnoticed alternative pathways at play here, why wouldn't they also have a connection to mood?

Maybe if you were in particular seeking a way to mimic exercise with drugs this kind of thing becomes more useful.




Though, conversely, if we can strongly associate a given stimulus or process with a respose, regardless of understanding the specific pathway(s), is that not useful information?

It was the basis of much practical knowledge for most of history.




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