I'm not really sure what the definition of an instrument is here, but many electronic artists are using Ableton to perform live. If were willing to call turntables an instrument then we need to call Ableton one as well. Quote from the popular BassMusic producer GJONES:
"What do you use to produce & perform?
I use Ableton Live for both. I use almost solely Ableton’s built in synths/effects in my productions. My live setup is a sort of DJ-style set, in that I mainly mix using 2 audio channels and then have several more channels of acapellas, drum loops, risers, 1 shots, drum samples, etc."
Even though you can use Ableton to 'perform live' this is rather raw. When I say 'as an instrument' I mean as the conduit to creativity. The primary creatives in music would have been songwriter/composer, lyricist, performer. Now it's moved into production and the mechanism is not a guitar or piano, it's a variety of digital tools upon which creativity/composition is performed.
"What do you use to produce & perform? I use Ableton Live for both. I use almost solely Ableton’s built in synths/effects in my productions. My live setup is a sort of DJ-style set, in that I mainly mix using 2 audio channels and then have several more channels of acapellas, drum loops, risers, 1 shots, drum samples, etc."
https://www.youredm.com/2014/02/13/feature-g-jones/