If you're building a tall apartment block you're already trusting your building regulations/safety practices to prevent disaster; having a bridge above you doesn't seem inherently more risky than having n floors of housing above you.
It's Genoa: sandwiched between sea and mountains, space is at a premium. Think of those lovely shots of Manarola and Cinque Terre, multiply them by a million, add one of Europe's biggest ports, and that's Genoa.
Not just a trainyard: reportedly the bridge runs above Ansaldo Energia, a big company that makes generators and turbines. So yeah, definitely not prime land, but still crowded.