Monday is strategy, ops & finance. (A lot of Mondays don't require that much in this area, so there's extra time for other high priority tasks.)
Tuesday is sales.
Wednesday is R&D.
Thursday is marketing.
Friday is catch-up. This is actually the most important part, I've found. I used to over(schedule) everything, so my week would look really productive on Monday morning, but come next Monday morning, most things were in a state of "not quite done". In many cases, getting 80-90% of the way there has the same result as doing nothing. It was very frustrating. (Add in having kids, with days off school, random illnesses, etc, and the chance of having your week go exactly according to plan drop close to 0.)
This lets me catch up on the "big rock" items that I'm behind on. It's not perfect, but the idea is that every week I'm moving things forward. If I get done "early", there are plenty of other important things to start on (my "upcoming list"), or maybe I just go work out or research something a bit out of the ordinary that doesn't fit in my normal schedule.
It's not a perfect plan or a perfect implementation, but it feels much better than what I did before, which was too much context switching.