For Clojure, I think it means native compilation, with fast startup times, and the ability to interop with Python, Ruby, or any of the other Graal languages. Not sure there would be an advantage to re-implementing a Clojure on Graal. Clojure is not an interpreted language like Ruby, JavaScript and Python is, so I don't think Graal adds as much benefit here.
For ClojureScript, it would mean full circle. You could run your ClojureScript back on the JVM, and have Java interop from it.