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Wow, that seems high -- 412,000 is 15% of the total number of American deaths in 2015 which was 2,712,630.

https://www.cdc.gov/nchs/nvss/deaths.htm

But that seems to be what they're claiming:

> Population attributable fractions were calculated to show the proportional reduction in all-cause mortality, cardiovascular disease mortality, and ischaemic heart disease mortality that would occur if recorded concentrations of lead in blood were reduced to 1·0 μg/dL or lower (≤0·048 μmol/L). The adjusted population attributable fraction for all-cause mortality was 18% (95% CI 10·9–26·1), equivalent to 412 000 (95% CI 250 000–598 000) deaths each year (table 2). Adjusted population attributable fractions were 28·7% (95% CI 15·5–39·5) for cardiovascular disease mortality and 37·4% (23·4–48·6) for ischaemic heart disease mortality, equivalent to 256 000 cardiovascular disease deaths and 185 000 ischaemic heart disease deaths annually (figure 3).




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