Depends on your reliance I suppose. Appears most of TimescaleDB's vendor-specific pieces are in the DDL area, but there are plenty of DML-specific extensions. I'm not saying TimescaleDB might not get to a level of maturity where I'd use it, I personally just can't justify it today. I've found DBs and ops/orchestration engines to be the most painful to move off from if you need to.
They also provide the most bang for the feature-complexity buck. (A DB is something you don't want to roll on your own, and you want to use the purpose-built one for your use case. A columnar store for time series, a scatter-gather SSD + random read optimized engine for hot OLTP, a fancy multi level cache/tier BLOB store for photos/files, CockroachDB for geo consistency, etcd for local consistent config, and so on.)
