At least in my experience, historians are rarely recommend for complex or ad-hoc queries. Typically you just pull the data (by tags) into another application and do your data processing there. It looks like in timeseriesdb lets you execute complex queries in the database. Historians typically only let you fetch data by tag and you need a metadata (e.g. asset management) framework on top to organize the data (e.g. give me avg temp every 5 minutes by sensor). It looks like with timeseriesdb you can have strings/text as fields within the timeseries table, which removes the need (to some degree) to join the data with a seperate metadata database.
I've also never heard of anybody using these commercial historians for time series data you'd see from non industrial processes (e.g. stock data, price tracking, GPS location of people or moving assets, time between clicks on a website,etc).
All that being said, OSISoft PI and AF have their warts, but OSISoft has been around for a while and PI has been battle tested in various industries (e.g. Oil & Gas, Manufacturing). It's closed source and you have to pay for it, so it's probably not attractive to startups and smaller companies. But it does come with a support organization if you need it and can pay for it. And IME data retrieval from PI is extremely performant!
Being transactional is orthogonal to being immutable. For example, if you want to ensure that a given set of writes is applied atomically, you would issue them in a transaction.
This is especially important if you are also dealing with metadata that you don't want to always denormalize into your time-series tables. If you don't insert it transactionally, you can also lose referential integrity between your time-series and relational (metadata) tables.
That's not always true. There are tons of cases where time-series data gets corrected later. It is true that time-series is INSERT-mostly but UPDATES do happen.