Register access isn't the issue. In the first example, this.Width and this.Height are accessing the Width and Height property of the current object. This requires a heap fetch on each iteration of the loop. There may be OS-specific nuances with automatic caching that I can't remember clearly enough to reliably mention.
If you can get rid of all heap lookups in your iterative loop, then you'll see a large speed boost if that was the bottleneck. Local variables exist on the stack, which tends to exist in the CPU cache when the current thread is active. https://msdn.microsoft.com/en-us/library/windows/desktop/ms6...
Unfortunately, method calls in C# have a much higher overhead than in C and C++. If you must do a method call in your loop, be sure to read this to see if your method can be inlined. Only very small methods of 32 IL bytes or less can be inlined: https://stackoverflow.com/questions/473782/inline-functions-...
If you can get rid of all heap lookups in your iterative loop, then you'll see a large speed boost if that was the bottleneck. Local variables exist on the stack, which tends to exist in the CPU cache when the current thread is active. https://msdn.microsoft.com/en-us/library/windows/desktop/ms6...
Unfortunately, method calls in C# have a much higher overhead than in C and C++. If you must do a method call in your loop, be sure to read this to see if your method can be inlined. Only very small methods of 32 IL bytes or less can be inlined: https://stackoverflow.com/questions/473782/inline-functions-...