It's ok to dislike something and recognize how poor it is compared to better implementations it helped inspire, but still respect what it did for us in the past.
Flash, Java Applets, and jQuery all changed the web for the better and were amazing things at one time. But we should move on.
For the most part for common tasks supporting IE10+, yes.
There are still some things it will do for you that can be tedious with vanilla and arguments could still be made to use it as a dependency. But imho, it should be treated more of as an optional dependency that you use when/if you need it, rather than a cross browser compatibility crutch.
http://youmightnotneedjquery.com/ helped me out quite a bit as I transitioned away from using it for day to day. It's not exactly 1-to-1, but it helped ease the initial pain.
Flash, Java Applets, and jQuery all changed the web for the better and were amazing things at one time. But we should move on.