Thanks for that - I'll have to have a look at that when I get back on my network.
As you say, there are many reasons why cancer isn't self - neo-antigens are just a facet of that. Are cancer associated antigens the same thing as cancer-testis antigens? To be honest, I've never really groked CTAGs - they don't make sense to me. Why does the thymus not expose T cells to them? Why does cancer produce them? To many questions..!
As you say, there are many reasons why cancer isn't self - neo-antigens are just a facet of that. Are cancer associated antigens the same thing as cancer-testis antigens? To be honest, I've never really groked CTAGs - they don't make sense to me. Why does the thymus not expose T cells to them? Why does cancer produce them? To many questions..!