You don't start with a salary and then choose a city. The city determines the salary. If you can find a salary at all, it's likely to be in a high COL city.
Of course I'd love to make $120k from somewhere that buys a nice house. That is, far as I can tell, not an option. I can save while living in a high COL city and then buy a house for cash in a low COL city, but I'd still need a job to pay property taxes/groceries/transportation. In cheap areas, the pickings are slim.