Those are the rates for something like Down's syndrome. Gross chromosomal abnormalities are mostly determined by maternal age.
Everyone has a few mutations in protein coding regions, and the number rises with paternal age. Most mutations are neutral or harmful.
More rolls of the dice to accumulate more (likely small) damage is probably going to hurt you.
The way it almost certainly works is people who have better genes (for socioeconomic success in our current society) have kids later and these kids inherit these traits....
However it would probably be better if the dad had the kids younger.
It's also easier for denovo mutations to cause mental rather than physical problems as the brain is very complex so there's more genes used and more to go wrong.
PS I'm a 37 year old bioinformatician expecting a little geek in a few months :)
Everyone has a few mutations in protein coding regions, and the number rises with paternal age. Most mutations are neutral or harmful.
More rolls of the dice to accumulate more (likely small) damage is probably going to hurt you.
The way it almost certainly works is people who have better genes (for socioeconomic success in our current society) have kids later and these kids inherit these traits....
However it would probably be better if the dad had the kids younger.
It's also easier for denovo mutations to cause mental rather than physical problems as the brain is very complex so there's more genes used and more to go wrong.
PS I'm a 37 year old bioinformatician expecting a little geek in a few months :)