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> “It’s a real paradigm shift, and undermines a great deal of what’s in the textbooks,” he said.

Sorry, but is this really that new? I've never been taught that the DNA strands coordinate with each other while replicating, so it seems quite possible that synthesis of each strand can be independent of each other.




When I did my Phd in bioinformatics about 10 years ago, most of the molecular biologists and biochemists I talked with expected that something similar to what these researchers found was what happened, but the details was of cause not known. Thus this is maybe the least surprising result they could get. In Kuhnian terms, this is puzzle-solving rather than a paradigm shift.


The "paradigm shift" is referring to the "stochastic" nature of replication, which apparently was not known before.


i was taught all the things they're saying in this press release ~20 years ago in biochem class.


It's a university press release. They're all written that way, unfortunately.




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