In Alastair Reynolds' Revelation Space series, there was a colonisation attempt before the main one in that series where fertilized embryoes were sent on ships with all they needed to rebuild civilisation. Turned out some fraction of the people born thusly became psychopaths and killed off all the rest, dooming the entire thing, so in the books all that is left is artifacts. I always found it a very nice touch and highly plausible that such an attempt failed spectacularly.
We already have that: at least 5-10% of the population is naturally born that way now. We try to socialize them out of it, which has some success, but for those who it doesn't, the dumb ones become hardened criminals, and the smart ones become politicians and CEOs.
This colonization idea needs to wait until we can figure out the genetic basis of sociopathy, and then we can genetically engineer it out of the fertilized embryos, and instead GE them to be much more interdependent and social than we are.
