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It's not just the improvement in spatial resolution, but in temporal resolution, too. The ability to stimulate specific subpopulations on millisecond timescales basically means the precision of our surgical techniques is now probably the main bottleneck to more sophisticated control (alongside our own understanding of the interactions of different neuronal circuits).

I'd say it's not so much a matter of "if" Deisseroth and his colleagues win so much as when.




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