As someone with the last name of Carp, I agree you shouldn't eat me! :p
(I had to make the joke,sorry)
I want to agree with you about "dumb bad luck." Unfortunately, your description of why turns the science question gears in my head if there is an epigenetic or genetic or a mixture of both (especially since this appears to be X linked? testoterone level linked? something along those lines?) What about maleness matters that leaves women nearly unaffected? Are there certain men more likely to be affected given that sushi has been around for like 30 years in the west, in some places longer, and the rates haven't risen dramatically yet.
And while on the surface it sounds like you have an awesome family tree, many people's families underdiscuss their family health in their family trees (mine is unusual in that we don't). In some cases old documents are misunderstood in terms of cause of death (eg: consumption used to be a thing) I don't know your family dynamics well, especially 5 generations back. Having an actual copy of your DNA in a database (and having a copy of your medical records in a super ideal world in safety deposit box for when they are older for essentially the same reason), basically ensures against questions later.
besides, you also have no idea what good genes/epigenetics that you never got to take advantage of that got passed down. Same probability principles hold, and as overall sequencing costs go down for the general population, there will be research in that area as well, and they might be interested in that as well
And you should really tweet about the fish - I actually didn't know about the parasite :/
(I had to make the joke,sorry)
I want to agree with you about "dumb bad luck." Unfortunately, your description of why turns the science question gears in my head if there is an epigenetic or genetic or a mixture of both (especially since this appears to be X linked? testoterone level linked? something along those lines?) What about maleness matters that leaves women nearly unaffected? Are there certain men more likely to be affected given that sushi has been around for like 30 years in the west, in some places longer, and the rates haven't risen dramatically yet.
And while on the surface it sounds like you have an awesome family tree, many people's families underdiscuss their family health in their family trees (mine is unusual in that we don't). In some cases old documents are misunderstood in terms of cause of death (eg: consumption used to be a thing) I don't know your family dynamics well, especially 5 generations back. Having an actual copy of your DNA in a database (and having a copy of your medical records in a super ideal world in safety deposit box for when they are older for essentially the same reason), basically ensures against questions later.
besides, you also have no idea what good genes/epigenetics that you never got to take advantage of that got passed down. Same probability principles hold, and as overall sequencing costs go down for the general population, there will be research in that area as well, and they might be interested in that as well
And you should really tweet about the fish - I actually didn't know about the parasite :/