I explicitly did not mention Gentoo - I know a bunch of people who run it in production. But, for anyone considering to do this - if you're running Gentoo, you're essentially building your own distro, which has massive advantages but is also a huge effort. You're now in charge of security updates, maintenance and Q&A. What if you're leaving the company? There are many Debian or Redhat admins, but good luck finding a Gentoo expert.