this requires individualized treatment based on the description which will make the implementation costly and impractical. They need to extract a piece of the tumor from the brain.
yes but thats only the first step in this case. then they need to prepare the individualized mRNA shot from there. How long it takes and how complex it is is another question.
Yes, most of the promise of mRNA with cancer is the prospect for individualized therapy. But individualized therapy intrinsically means you're going to be a doing a patient-specific manufacturing step.
Sequencing and RNA synthesizing are widely available commercial services at this point, though not cheap.
There's a lot of magic to take mRNA and formulate it to last in the human body and go and do what you want, but it isn't likely to be the costly part of all of this if there's some small volume of people being treated this way.