Looking forward to someone adapting this for Obsidian and other similar tools. As a low-effort user of Obsidian I would love to reap the benefits of appropriate knowledge graphs, but don't want to put that much effort into creating one myself.
20 years and still no API. In my past as an academic I've tried several times to build systems to depend on Scholar and was always taken aback by the lack of an API. I get it was not to be swallowed whole by other publishers etc, but that has reduced the potential of the product.
The gain you get from implanting as soon as possible is massive compared to waiting it off. No one truly considering it should be waiting and instead actually pushing for an implant as soon as possible.
For our son, in the UK in 2019, they asked us to wait until our son was one year old. We insisted to have him implanted as soon as possible and us being ready to do it at 6 months (possible already in US). We managed to do at 7 months only switching surgeon to a much younger and keen surgeon that was pushing to lower the implantable age in children on the back of the massive benefits gained and very similar complication rate as close age brackets.
Our son is currently in mainstream school and doing brilliantly.
Hi, I have an 8 week old deaf daughter in the UK and id love to talk to you about your experience getting the cochlear implant, particularly how you were able to get it so early
If you're happy to could you get in touch via my email in bio? Thanks
Great idea. Whish this was also expanded to the UK, have exactly the same exact problem here. I keep looking at prices on Amazon and have managed to snatch a few great deals in the past, but having something like this would make it an effortless shopping
Still have one of those tucked away at my father’s place. He used to use it at the beginning of his career to run calculations for engineering structural computations before Acca and other similar softwares (in Italy due to very active seismic activity you need to run these sorts of calculations also for very small structures).
Most likely raise of sea level? Anecdotally, I am originally from the south of Italy and at different stages both my father and grandfather mentioned to me that the seashore was much further away than the current one with the one my father recalled midway between the one my grand father remembered and the one we have now.
For those interested in the relationship between humans, their supporting infrastructure (not just highways, but also the cities and everything around those), and nature specifically from a perspective of the Autostrada del Mediterraneo: I can suggest this book: www.store.rubbettinoeditore.it/catalogo/presente-infinito/ which tries (just visually through photos) to demonstrate that complicated and precarious relationship.
I was very curious as this has now happened to me directly (which led me to search the web in the first instance). My current situation is tinnitus has severely increased. And it is much worse if I wear the AirPods (though in this case I can't objectively say/measure any potential bias I might now have after seeing the page).
I live in the UK and PFOAs have showed up in testing around the area we live in. At 14.5ng/l, they already exceed the safety level in US and EU, 10ng/l. However the threshold level in water in the UK is 100ng/l so :politician-shrugging:
You are lucky to know ahead of time about your respective mutations. We didn’t (no family history and both asymptomatic carriers) and my son was born bilateral profoundly deaf (connexin 26). We have chosen the path of cochlear implant (which is an amazing technology). We are both looking forward to seeing advancements in therapies for GJB2 mutations sparing many parents (and children) what we have been through. However, corrective therapy for GJB2 might require much earlier discovery of the issue and earlier administration I believe, as usually those variants affect actual physical growth of hair cells in the cochlea.
Yes, we are fortunate to live in a time where the technology is advanced enough to do this. My wife and I got ourselves sequenced before we decided to have a child (that's just data nerd nonsense) and when we discovered this we went through the whole shebang.
I believe it's the OTOF variant that affects the cilia growth. Without intending to give any hope (because I am a software engineer in the end, not a geneticist), perhaps the GJB2 variants can be fixed because they regulate electrical function. Who can tell. Decibel's AAV.103 will go into clinical trial in the next couple of years. https://www.decibeltx.com/pipeline/
The cochlear implant is wonderful tech. Before we had enough embryos, it was something that we discussed with our genetic counselor. Is your son still very young? Some of the OTOF treatments were in older children (in China). Perhaps the GJB2 treatments could be too. I am hopeful that even if your children and mine can't access this treatment, we will make this condition repairable shortly after birth from our generation onwards.
