Not in the short term. Smoke and suchlike very computationally intensive to simulate well. I threw together a very rough version of this in After Effects after reading the authors comments on the TNW page (by very rough I mean just loading a bunch of similar plugins and specifying crude parameters) in order to get an idea of how long it might take to render 3 minutes' worth, the result being 'several hours' on a fairly decent quad core machine - and clearly the author has put in a good deal more work on this.
Now you could offload a lot of this work to the GPU with some planning, and employ numerous little tricks and dare-i-say-it hacks, but I'd say the earliest you'll see this running in real time is when the 2015 32-core Mac Pro hits the streets.
Now you could offload a lot of this work to the GPU with some planning, and employ numerous little tricks and dare-i-say-it hacks, but I'd say the earliest you'll see this running in real time is when the 2015 32-core Mac Pro hits the streets.
edit: I'm being pessimistic. 2012 is more likely.