People have made this argument for ClojureScript as well. In the case of ClojureScript the benefits are considerably less clear as we rely on the ability of Google Closure to do fairly amazing optimizations on the generated JavaScript source.
That said I'd love to see a serious Clojure-in-Clojure targeting LLVM.
That said I'd love to see a serious Clojure-in-Clojure targeting LLVM.