That study found a small effect size compared to placebo, and a large placebo response.
That seems consistent with OP's comment of "SSRIs...mostly don't differ from placebo" (emph added).
Also not addressed in the paper is the fact that SSRIs and SNRIs have well-known and pronounced side effects, with make it questionable whether double-blind studies are really fully blinded.
That seems consistent with OP's comment of "SSRIs...mostly don't differ from placebo" (emph added).
Also not addressed in the paper is the fact that SSRIs and SNRIs have well-known and pronounced side effects, with make it questionable whether double-blind studies are really fully blinded.