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> The dominant strain of Covid in South Africa is different and existing vaccines are far less effective at countering due to changes in the spike protein which these vaccines target.

Only Johnson&Johnson data may say something about it for real. Novavax's investigation was underpowered (4000 people, wide confidence intervals), and this one is even more so.

The rest of the evidence comes from antibody neutralization assays in vitro, which although very useful they are not representative of the whole immune response.




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