My best experience is with Ember and Ember-CLI where the build process is pre-defined and laid out for you, and the requirements to start a project are: have node + bower + ember-cli installed globally, type `ember new project-name`, `npm install` it to get the dependencies, then start writing ES6. Type `ember build` when you're ready to create a browser-ready artifact. As far as tooling and build processes go, IMO it's less cumbersome than setting up a proper Go environment and cross-compiling to different platforms.
