On Linux (Gnome), you can drag and drop from the save dialog in the Take Screenshot app so you never actually have to save it. I just tested it with GMail and it works like a charm.
That's brilliant! It's such a simple feature, but such a huge step in UI magic.
I always hated those needless extra steps in screenshotting. And then two months later your Desktop is full of things you forgot to delete and you had to figure out why you had ever needed a screenshot of top in the first place...